Cancer Research – PCR Panels
Oncology Targets
BCR-ABL Fusion
Chronic myelogenous leukemia
Quantify fusions between the breakpoint cluster region (BCR) gene and the tyrosine-protein kinase gene ABL1
ESR1
Breast cancer
Detect mutations in the estrogen receptor 1 gene
IDH1 and IDH2
Acute myeloid leukemia, glioma, cholangiocarcinoma and others
Test for mutations in genes that code for isocitrate dehydrogenase 1 and 2
KRAS
Lung, colorectal, and pancreatic cancers
Assays for the G12/G13 mutations in the Ki-ras2 Kirsten rat sarcoma viral oncogene homolog gene
NPM1-W288FS*12 Insertion Detection
Acute myeloid leukemia
Identify the most common exon 12 mutation that causes
cytoplasmic sequestration of nucleophosmin 1
EGFR
Lung, breast, and glioblastoma cancers
Identify 30 actionable mutations in exons 18-21 of the EFGR gene
Key Benefits
Detect as few as 3 copies of tumor DNA or RNA and genotype samples with low variant allele frequency
Leverage our GT-Plex™ technology to amplify more targets in each assay, saving you time and money
Assay your samples with validated kits that include all necessary primers, probes, and controls
Eliminate interference from PCR inhibitors using dPCR technology
GT-Plex™ Multiplexed Digital PCR Kits
Multiplexed
Save time and money by testing multiple mutations in a single reaction
Targeted
Assay mutations in EGFR and KRAS with GT-Plex™ technology
Versatile
Use our dPCR Kits with Bio-Rad QX100™, QX200™, QX600™, QIAGEN QIAcuity®, and other RT-PCR platforms
(PATENTS AND PATENTS-PENDING)
For research use only. Not for use in diagnostic procedures.
GT-Plex™ EGFR Multiplex Digital PCR Assay
Key Advantages:
- Targets over 30 actionable mutations in the EGFR gene spanning exons 18 through 21
- Validated for 11 targets, including 8 TKI-sensitive and 3 TKI-resistant mutations
- Optimized for the Bio-Rad QX100™, QX200™, QX600™, and QIAGEN QIAcuity®
- Demonstrates excellent sensitivity and robust performance over a broad dynamic range
- Eliminates interference from PCR inhibitors compared to RT-qPCR
- Multiplex for faster throughput and lower reagent cost
- Includes all necessary controls
- Compatible with FFPE and cfDNA/ctDNA samples