Cancer Research – PCR Panels

Oncology Targets

BCR-ABL Fusion
Chronic myelogenous leukemia
Quantify fusions between the breakpoint cluster region (BCR) gene and the tyrosine-protein kinase gene ABL1

ESR1
Breast cancer
Detect mutations in the estrogen receptor 1 gene

IDH1 and IDH2

Acute myeloid leukemia, glioma, cholangiocarcinoma and others
Test for mutations in genes that code for isocitrate dehydrogenase 1 and 2

KRAS
Lung, colorectal, and pancreatic cancers
Assays for the G12/G13 mutations in the Ki-ras2 Kirsten rat sarcoma viral oncogene homolog gene

NPM1-W288FS*12 Insertion Detection
Acute myeloid leukemia
Identify the most common exon 12 mutation that causes
cytoplasmic sequestration of nucleophosmin 1

EGFR
Lung, breast, and glioblastoma cancers
Identify 30 actionable mutations in exons 18-21 of the EFGR gene

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Key Benefits

Sensitive

Detect as few as 3 copies of tumor DNA or RNA and genotype samples with low variant allele frequency

Multiplexed

Leverage our GT-Plex™ technology to amplify more targets in each assay, saving you time and money

Easy to Use

Assay your samples with validated kits that include all necessary primers, probes, and controls

Robust

Eliminate interference from PCR inhibitors using dPCR technology

GT-Plex™ Multiplexed Digital PCR Kits

Multiplexed
Save time and money by testing multiple mutations in a single reaction

Targeted
Assay mutations in EGFR and KRAS with GT-Plex™ technology

Versatile
Use our dPCR Kits with Bio-Rad QX100™, QX200™, QX600™, QIAGEN QIAcuity®, and other RT-PCR platforms

(PATENTS AND PATENTS-PENDING)
For research use only. Not for use in diagnostic procedures.

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GT-Plex™ EGFR Multiplex Digital PCR Assay

Key Advantages:

  • Targets over 30 actionable mutations in the EGFR gene spanning exons 18 through 21
  • Validated for 11 targets, including 8 TKI-sensitive and 3 TKI-resistant mutations
  • Optimized for the Bio-Rad QX100™, QX200™, QX600™, and QIAGEN QIAcuity®
  • Demonstrates excellent sensitivity and robust performance over a broad dynamic range
  • Eliminates interference from PCR inhibitors compared to RT-qPCR
  • Multiplex for faster throughput and lower reagent cost
  • Includes all necessary controls
  • Compatible with FFPE and cfDNA/ctDNA samples
For research use only. Not for use in diagnostic procedures.
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GT-Plex™ Multiplex Digital PCR Assays Show Robust Performance Across a Broad Linear Dynamic Range

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Our All-in-One PCR Test Kits

All GTM dPCR test kits include all of the validated primers, probes, and positive and negative controls required for your assay

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Popular Oncology Research Kits

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dPCR KRAS G12C;G12 Assay Kit for the Bio-Rad QX200®
(Cat# 100410) The dPCR KRAS G12C;G12 Assay Kit for the Bio-Rad QX200® Droplet Digital® PCR System is a Research-Use Only (RUO) molecular reagent kit containing all primers, probes, and controls for the detection and relative abundance of the G12C mutation found in the human KRAS gene. This duplexed assay contains a FAM probe that targets […]
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dPCR NPM1-W288fs*12 Insertion Detection Assay Kit for the Bio-Rad QX200®
(Cat# 100400) The dPCR NPM1-W288fs*12 Insertion Detection Assay Kit for the QX200® System is a molecular reagent kit containing all primers, probes, and controls for the detection of NPM1-W288fs*12 mutations found in Acute Myeloid Leukemia (AML). While this test does not target every mutation present in NPM1, it has been validated for the detection of […]
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dPCR EGFR Actionable Mutations Panel Assay Kit for the Bio-Rad QX200®
(Cat# 100435) The dPCR EGFR Actionable Mutations Panel Assay Kit for the Bio-Rad QX200® Droplet Digital® PCR System is a Research-Use Only (RUO) patent-pending molecular reagent kit containing all primers, probes, and controls for the detection and relative abundance of common activating mutations found in the human EGFR gene. Contains enough material for 50 reactions.
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Our Oncology Assays Are Optimized for QIAGEN, Roche, and Bio-Rad Digital PCR Platforms

Roche Digital LightCycler®
QIAGEN QIAcuity® Digital PCR System
Bio-Rad QX200™ & QX600™ Droplet Digital PCR System
“GT Molecular has had the most informative and thought-out instructions that have been included with the assay kits we have tried.”
Christine Laba | Oakland University

GT Molecular dPCR Assay Advantages

Increased Sensitivity
Detect low-copy number transcripts with greater sensitivity than RT-qPCR
Multiplex Technology
Assay several targets in each dPCR reaction, saving you time and money
Decreased Inhibitor Interference
Small reactions dilute the effects of any PCR inhibitors present in a sample

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